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fmblab

Enchancment of immunodetection of the transcription issue C/EBP homologous protein

Enchancment of immunodetection of the transcription issue C/EBP homologous protein by western blot. Accumulation of misfolded proteins throughout the endoplasmic reticulum (ER) induces an unfolded protein response (UPR) that both restores homeostasis or triggers apoptosis in case of adaptation failure. The three activated branches of UPR result in IRE1-, PERK- and ATF6– dependent transcriptional induction of the […]