Impact on Hematopoietic Stem Cell Biology

fmblab

Biomaterial-Driven Immunomodulation: Cell Biology-Based Strategies to Mitigate Severe Inflammation and Sepsis

Inflammation is an essential component of a wide variety of disease processes and oftentimes can increase the deleterious effects of a disease. Finding ways to modulate this essential immune process is the basis for many therapeutics under development and is a burgeoning area of research for both basic and translational immunology.

In addition to developing therapeutics for cellular and molecular targets, the use of biomaterials to modify innate and adaptive immune responses is an area that has recently sparked significant interest. In particular, immunomodulatory activity can be engineered into biomaterials to elicit heightened or dampened immune responses for use in vaccines, immune tolerance, or anti-inflammatory applications.

Importantly, the inherent physicochemical properties of the biomaterials play a significant role in determining the observed effects. Properties including composition, molecular weight, size, surface charge, and others affect interactions with immune cells (i.e., nano-bio interactions) and allow for differential biological responses such as activation or inhibition of inflammatory signaling pathways, surface molecule expression, and antigen presentation to be encoded.

Numerous opportunities to open new avenues of research to understand the ways in which immune cells interact with and integrate information from their environment may provide critical solutions needed to treat a variety of disorders and diseases where immune dysregulation is a key inciting event. However, to elicit predictable immune responses there is a great need for a thorough understanding of how the biomaterial properties can be tuned to harness a designed immunological outcome.

This review aims to systematically describe the biological effects of nanoparticle properties-separate from additional small molecule or biologic delivery-on modulating innate immune cell responses in the context of severe inflammation and sepsis. We propose that nanoparticles represent a potential polypharmacological strategy to simultaneously modify multiple aspects of dysregulated immune responses where single target therapies have fallen short for these applications.

This review intends to serve as a resource for immunology labs and other associated fields that would like to apply the growing field of rationally designed biomaterials into their work.

fmblab
fmblab

Tetrodotoxin (TTX) ELISA Test Kit

DEIANJ48 96T
EUR 1950
Description: This test kit is for the quantitative detection of Tetrodotoxin in the tissue, liver, fish.

Frit Kit

FRIT-KIT 1each
EUR 148.8
Description: Kit to create frits in capillaries. Includes formamide, Kasil-1, Kasil-1624 and a cleaving tool.

Column Packing Kit

PACK-KIT 1pack
EUR 1242
Description: Column packing kit for pressure cells. Includes: HPREG regulator, TBNG10 tubing, CAP-75 capillary, and STRB5X2 stir bar.

Porcine Parvovirus Antibody Elisa Test Kit

767-LSY-30009 192 Wells/kit
EUR 382

PCR Mycoplasma Detection Kit

M034-Kit Kit
EUR 319.2

FERR ( Ferritin) ELISA test

7 96T/Box Ask for price
  • Area of application: Hormone testing
Description: ELISA based test for quantitative detection of FERR ( Ferritin)

Syphilis Antibody ELISA test

100 96T/Box Ask for price
  • Area of application: Blood Screening
Description: ELISA based test for quantitative detection of Syphilis Antibody

TSH (Thyrotrophin) ELISA test

14 96T/Box Ask for price
  • Area of application: Hormone testing
Description: ELISA based test for quantitative detection of TSH (Thyrotrophin)

PRL (Prolactin) ELISA test

4 96T/Box Ask for price
  • Area of application: Hormone testing
Description: ELISA based test for quantitative detection of PRL (Prolactin)

E2 (Estradiol) ELISA test

5 96T/Box Ask for price
  • Area of application: Hormone testing
Description: ELISA based test for quantitative detection of E2 (Estradiol)

PROG (Progesterone) ELISA test

20 96T/Box Ask for price
  • Area of application: Hormone testing
Description: ELISA based test for quantitative detection of PROG (Progesterone)

TESTO (Testosterone) ELISA test

19 96T/Box Ask for price
  • Area of application: Hormone testing
Description: ELISA based test for quantitative detection of O (osterone)

T3 (Triiodothyronine) ELISA test

15 96T/Box Ask for price
  • Area of application: Hormone testing
Description: ELISA based test for quantitative detection of T3 (Triiodothyronine)

T4 (Thyroxine) ELISA test

16 96T/Box Ask for price
  • Area of application: Hormone testing
Description: ELISA based test for quantitative detection of T4 (Thyroxine)

CA72-4 ELISA test

24 96T/Box Ask for price
  • Area of application: Hormone testing
Description: ELISA based test for quantitative detection of CA72-4

HBcAb Sandwich ELISA test

95 96T/Box Ask for price
  • Area of application: Hepatitis testing
Description: ELISA based test for quantitative detection of HBcAb Sandwich

Accu-Tell COVID-19 IgG/IgM Rapid Test

GEN-B352-20tests 20 tests
EUR 283.2
Description: A rapid test for detection of antibodies (IgG and IgM) for 2019-nCoV, the novel Coronavirus from the Wuhan strain. The test is easy to perform, takes 10 minutes to provide reliable results and is higly specific to the 2019-nCoV Coronavirus.

Accu-Tell COVID-19 IgG/IgM Rapid Test

GEN-B352-40tests 40 tests
EUR 385.2
Description: A rapid test for detection of antibodies (IgG and IgM) for 2019-nCoV, the novel Coronavirus from the Wuhan strain. The test is easy to perform, takes 10 minutes to provide reliable results and is higly specific to the 2019-nCoV Coronavirus.

Melamine Rapid Test Kit

abx092011-50tests 50 tests
EUR 444
  • Shipped within 5-12 working days.

NDV rapid test kit

RG15-03 1 box
EUR 166.86
Description: Please check the datasheet of NDV rapid test kit before using the test.

Staphyloslide Latex Test Kit

240915 PK100
EUR 272.46

Hach Test Kit CYANIDE

LCK315 EACH
EUR 144.28

Hach Test Kit FLUORIDE

LCK323 EACH
EUR 136.62

Hach Test Kit COPPER

LCK329 EACH
EUR 178.75

Hach Test Kit NICKEL

LCK337 EACH
EUR 183.86

Hach Test Kit SULPHIDE

LCK653 EACH
EUR 163.43

Elga Chlorine Test Kit

WAT4098 EACH
EUR 385.32

?-HCG (Human chorionic gonadotropin) ELISA test

1 96T/Box Ask for price
  • Area of application: Hormone testing
Description: ELISA based test for quantitative detection of ?-HCG (Human chorionic gonadotropin)

HGH (Human chorionic gonadotropin) ELISA test

22 96T/Box Ask for price
  • Area of application: Hormone testing
Description: ELISA based test for quantitative detection of HGH (Human chorionic gonadotropin)

NOVATest IgG/IgM Antibody Rapid Test Kit (NOVA Test)

UNCOV-40 40 Tests
EUR 115

Cas9 Protein and T7 gRNA SmartNuclease Synthesis Kit

CAS400A-KIT 1 kit (10 rxn)
EUR 1332
  • Category: Cas9

Pesticide Kit Containing All 10 Multi-Compound Mixes

SPXPR-KIT 1ML
EUR 1923.18

Test product

testtt 0 Ask for price

CMV-hspCas9-T2A-Puro SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit

CASLV100PA-KIT 1 Kit
EUR 1358.4
  • Category: Cas9

CMV-hspCas9-EF1-GFP SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit

CASLV105PA-KIT 1 Kit
EUR 1358.4
  • Category: Cas9

MSCV-hspCas9-T2A-Puro SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit

CASLV120PA-KIT 1 Kit
EUR 1358.4
  • Category: Cas9

MSCV-hspCas9-EF1-GFP SmartNuclease Lentivector Plasmid + LentiStarter Packaging Kit

CASLV125PA-KIT 1 Kit
EUR 1358.4
  • Category: Cas9

Human toluidine Red Unheated Serum Test (TRUST) ELISA Kit

abx257506-96tests 96 tests
EUR 764.4
  • Shipped within 5-12 working days.

Multiplex gRNA Kit + EF1-T7-hspCas9-H1-gRNA linearized SmartNuclease vector

CAS700A-KIT 10 rxn
EUR 1358.4
  • Category: Cas9

Multiplex gRNA Kit + CAG-T7-hspCas9-H1-gRNA linearized SmartNuclease vector

CAS720A-KIT 10 rxn
EUR 1358.4
  • Category: Cas9

Multiplex gRNA Kit + CMV-T7-hspCas9-H1-gRNA linearized SmartNuclease vector

CAS740A-KIT 10 rxn
EUR 1358.4
  • Category: Cas9

T7 gRNA SmartNuclease Synthesis Kit (includes CAS510A-1 & T7 IVT synthesis reagents)

CAS510A-KIT 1 Kit
EUR 966
  • Category: Cas9

NOVATest Antigen Rapid Test Kit (For Single Use) (NOVA Test)

nCov-500-01 1T
EUR 162

Cas9 Nickase: CMV-hspCas9(D10A)-T2A-Puro SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit

CASLV200PA-KIT 1 Kit
EUR 1358.4
  • Category: Cas9

Cas9 Nickase: CMV-hspCas9(D10A)-EF1-GFP SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit

CASLV205PA-KIT 1 Kit
EUR 1358.4
  • Category: Cas9

Cas9 Nickase: MSCV-hspCas9(D10A)-T2A-Puro SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit

CASLV220PA-KIT 1 Kit
EUR 1358.4
  • Category: Cas9

Cas9 Nickase: MSCV-hspCas9(D10A)-EF1-GFP SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit

CASLV225PA-KIT 1 Kit
EUR 1358.4
  • Category: Cas9

Multiplex gRNA Kit + Cas9 Nickase: EF1-T7-hspCas9-nickase-H1-gRNA linearized SmartNickase vector

CAS750A-KIT 10 rxn
EUR 1358.4
  • Category: Cas9

Multiplex gRNA Kit + Cas9 Nickase: CAG-T7-hspCas9-nickase-H1-gRNA linearized SmartNickase vector

CAS770A-KIT 10 rxn
EUR 1358.4
  • Category: Cas9

Multiplex gRNA Kit + Cas9 Nickase: CMV-T7-hspCas9-nickase-H1-gRNA linearized SmartNickase vector

CAS790A-KIT 10 rxn
EUR 1358.4
  • Category: Cas9

Cas9 SmartNuclease Extra Ligation Kit [includes 5x ligation buffer (10 ul) and Fast ligase (2.5ul)]

CAS9LIG-KIT 1 Kit
EUR 183.6
  • Category: Cas9

FSH (Human Follicle-stimulating hormone) ELISA test

3 96T/Box Ask for price
  • Area of application: Hormone testing
Description: ELISA based test for quantitative detection of FSH (Human Follicle-stimulating hormone)

AFP (Alpha fetoprotein) ELISA test

6 96T/Box Ask for price
  • Area of application: Hormone testing
Description: ELISA based test for quantitative detection of AFP (Alpha fetoprotein)

CA199 (Cancer antigen) ELISA test

13 96T/Box Ask for price
  • Area of application: Hormone testing
Description: ELISA based test for quantitative detection of CA199 (Cancer antigen)

LH (Luteinizing Hormone) ELISA test

2 96T/Box Ask for price
  • Area of application: Hormone testing
Description: ELISA based test for quantitative detection of LH (Luteinizing Hormone)

CA153 (Cancer antigen) ELISA test

12 96T/Box Ask for price
  • Area of application: Hormone testing
Description: ELISA based test for quantitative detection of CA153 (Cancer antigen)

CA125 (Cancer antigen) ELISA test

11 96T/Box Ask for price
  • Area of application: Hormone testing
Description: ELISA based test for quantitative detection of CA125 (Cancer antigen)

CA50 (Cancer antigen) ELISA test

10 96T/Box Ask for price
  • Area of application: Hormone testing
Description: ELISA based test for quantitative detection of CA50 (Cancer antigen)

FT4 (Free thyroxine) ELISA test

18 96T/Box Ask for price
  • Area of application: Hormone testing
Description: ELISA based test for quantitative detection of FT4 (Free thyroxine)

FT3 (Free triiodothyronine) ELISA test

17 96T/Box Ask for price
  • Area of application: Hormone testing
Description: ELISA based test for quantitative detection of FT3 (Free triiodothyronine)

HEV antibody IgM ELISA test

92 96T/Box Ask for price
  • Area of application: Hepatitis testing
Description: ELISA based test for quantitative detection of HEV antibody IgM

CEA (Cancer antigen) ELISA test

9 96T/Box Ask for price
  • Area of application: Hormone testing
Description: ELISA based test for quantitative detection of CEA (Cancer antigen)

HAV antibody IgM ELISA test

75 96T/Box Ask for price
  • Area of application: Hepatitis testing
Description: ELISA based test for quantitative detection of HAV antibody IgM

Claritas PPT Grade Minerals Testing Kit for ICP-MS 1000 ug/mL (1000 ppm) 6 each 30mL

SPXMT-KIT 30ML
EUR 237.12

Human Echovirus (ECHO) IgM Rapid Test Kit

abx092093-20tests 20 tests
EUR 326.4
  • Shipped within 5-12 working days.

Human Toxoplasma (TOX) IgG Rapid Test Kit

abx092098-20tests 20 tests
EUR 260.4
  • Shipped within 5-12 working days.

Melamine (MEL) Rapid Test Kit

abx092057-50tests 50 tests
EUR 444
  • Shipped within 5-12 working days.

Clenbuterol (CLE) Rapid Test Kit

abx092058-50tests 50 tests
EUR 292.8
  • Shipped within 5-12 working days.

Ractopamine (RAC) Rapid Test Kit

abx092059-50tests 50 tests
EUR 292.8
  • Shipped within 5-12 working days.

Salbutamol (SAL) Rapid Test Kit

abx092060-50tests 50 tests
EUR 292.8
  • Shipped within 5-12 working days.

Tetracycline (TCs) Rapid Test Kit

abx092063-50tests 50 tests
EUR 477.6
  • Shipped within 5-12 working days.

Sulfonamides (Sas) Rapid Test Kit

abx092064-40tests 40 tests
EUR 477.6
  • Shipped within 5-12 working days.

Quinolones (QNs) Rapid Test Kit

abx092065-40tests 40 tests
EUR 477.6
  • Shipped within 5-12 working days.

Ciprofloxacin (CPFX) Rapid Test Kit

abx092066-50tests 50 tests
EUR 477.6
  • Shipped within 5-12 working days.

Quinolones (QNs) Rapid Test Kit

abx092067-40tests 40 tests
EUR 477.6
  • Shipped within 5-12 working days.

Brucella Antibody Rapid Test Kit

abx092069-40tests 40 tests
EUR 427.2
  • Shipped within 5-12 working days.

Antibody ISOTYPING TEST KIT (OKSA11303)

OKSA11303 10 Tests
EUR 936
Description: Description of target: MOUSE MONOCLONAL ANTIBODY ISOTYPING TEST KIT;Species reactivity: Mouse;Application: IS;Assay info: ;Sensitivity:

PCRAgH5 AIV Detection Test Kit

PD55-02 1 kit
EUR 1082.96
Description: Please check the datasheet of PCRAgH5 AIV Detection Test Kit before using the test.

Rapid Leishmania Ab Test Kit

RB2104 1 box
EUR 152.4
Description: Please check the datasheet of Rapid Leishmania Ab Test Kit before using the test.

Rapid PED Ag Test Kit

RG14-01 1 box
EUR 191.88
Description: Please check the datasheet of Rapid PED Ag Test Kit before using the test.

Thermal Test Film Starter Kit

PCR0892 EACH
EUR 275.88

Thermal Test Film Roll Kit

PCR0894 EACH
EUR 234.84

Hanna Test Kit Chlorine Free

WAT1572 EACH
EUR 30.78

Penicillin Drug Stability Test Kit

PST100 100 assays
EUR 231.22
Description: This product includes 0.5 ml of the 10 x PST dye for 100 assays using 96-well plates or micro-cuvettes.

Liposome Plasma Stability Test Kit

SPS20 20 columns
EUR 234.99
Description: This product includes 20 spin-columns for liposome stability studies in plasma

PinPoint-FC 293T Platform Kit for Targeted Gene Insertion (includes PIN320A-1, PIN200A-1, PIN510A-1 & PIN600A-1)

PIN320A-KIT 1 Kit
EUR 5929.2
  • Category: PinPoint Integrase Tools

Claritas PPT Grade Heavy Metals Testing Kit for ICP-MS 1000 ug/mL (1000 ppm) 6 each 30mL

SPXHM-KIT 30ML
EUR 245.1

PinPoint-FC Murine iPSC Platform Kit for Targeted Gene Insertion (includes PIN340iPS-1, PIN200A-1, PIN510A-1 & PIN600A-1)

PIN340iPS-KIT 1 Kit
EUR 5929.2
  • Category: PinPoint Integrase Tools

2019-nCoV IgG/IgM Rapid Test Cassette (Whole Blood/Serum/Plasma)

GEN-402-25tests 25 tests
EUR 292.8
Description: A rapid test for detection of antibodies (IgG and IgM) for 2019-nCoV, the novel Coronavirus from the Wuhan strain. The test is easy to perform, takes 10 minutes to provide reliable results and is higly specific to the 2019-nCoV Coronavirus.

AAVS1 Safe Harbor Targeting Vector 2.0 - All-Purpose Donor (AAVS1-SA-puro-MCS), Complete Kit with CAS601A-1 (Cas9 SmartNuclease AAVS1-gRNA Targeting Vector) and GE640PR-1 (Junction PCR Primer Mix to confirm AAVS1 integration site)

GE620A-KIT 1 kit
EUR 2558.4
  • Category: Gene Editing

AAVS1 Safe Harbor Targeting Vector 2.0 - GOI Knock-in Donor (AAVS1-SA-puro-EF1-MCS), Complete Kit with CAS601A-1 (Cas9 SmartNuclease AAVS1-gRNA Targeting Vector) and GE640PR-1 (Junction PCR Primer Mix to confirm AAVS1 integration site)

GE622A-KIT 1 kit
EUR 2558.4
  • Category: Gene Editing

AAVS1 Safe Harbor Targeting Vector 2.0 - Reporter Knock-in Donor (AAVS1-SA-puro-MCS-GFP), Complete Kit with CAS601A-1 (Cas9 SmartNuclease AAVS1-gRNA Targeting Vector) and GE640PR-1 (Junction PCR Primer Mix to confirm AAVS1 integration site)

GE624A-KIT 1 kit
EUR 2558.4
  • Category: Gene Editing

DNASE TEST AGAR

D04-101-10kg 10 kg Ask for price

DNASE TEST AGAR

D04-101-2Kg 2 Kg Ask for price

DNASE TEST AGAR

D04-101-500g 500 g Ask for price

DERMATOPHYTE TEST AGAR

D04-107-10kg 10 kg
EUR 1018.8

DERMATOPHYTE TEST AGAR

D04-107-2Kg 2 Kg
EUR 268.8

4D Cell Biology: Adaptive optics lattice light-sheet imaging and AI powered big data processing of live stem cell-derived organoids

New methods in stem cell 3D organoid tissue culture, advanced imaging, and big data image analytics now allow tissue-scale 4D cell biology but currently available analytical pipelines are inadequate for handing and analyzing the resulting gigabytes and terabytes of high-content imaging data. We expressed fluorescent protein fusions of clathrin and dynamin2 at endogenous levels in genome- edited human embryonic stem cells, which were differentiated into intestinal epithelial organoids.

Lattice light-sheet imaging with adaptive optics (AO-LLSM) allowed us to image large volumes of these organoids (70 × 60 × 40 μm xyz) at 5.7 s/frame. We developed an open-source data analysis package termed pyLattice to process the resulting large (∼60 Gb) movie data sets and to track clathrin-mediated endocytosis (CME) events.

We then expressed fluorescent protein fusions of actin and tubulin in genome-edited induced human pluripotent stem cells, which were differentiated into human cortical organoids. Using the AO-LLSM mode on the new MOSAIC (Multimodal Optical Scope with Adaptive Imaging Correction) allowed us to image neuronal migration deep in the organoid. We augmented pyLattice with a deep learning module and used it to process the brain organoid data.

Common Sources of Inflammation and Their Impact on Hematopoietic Stem Cell Biology

Purpose of review: Inflammatory signals have emerged as critical regulators of hematopoietic stem cell (HSC) function. Specifically, HSCs are highly responsive to acute changes in systemic inflammation and this influences not only their division rate but also their lineage fate. Identifying how inflammation regulates HSCs and shapes the blood system is crucial to understanding the mechanisms underpinning these processes, as well as potential links between them.

Recent findings: A widening array of physiologic and pathologic processes involving heightened inflammation are now recognized to critically affect HSC biology and blood lineage production. Conditions documented to affect HSC function include not only acute and chronic infections but also autoinflammatory conditions, irradiation injury, and physiologic states such as aging and obesity.

Summary: Recognizing the contexts during which inflammation affects primitive hematopoiesis is essential to improving our understanding of HSC biology and informing new therapeutic interventions against maladaptive hematopoiesis that occurs during inflammatory diseases, infections, and cancer-related disorders.

SKOV-3/Luc Cell Line
AKR-232 1 vial
EUR 686.4
Description: SKOV-3/Luc Cell Line stably expresses luciferase and otherwise exhibits the same characteristics of the parental cell line.
MCF-7 cells
C0006008 One Frozen vial
EUR 546
cDNA from Human Tumor Cell Line: MCF 7
C1255830 40 reactions
EUR 451.2
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.
Human Mcf-7 Whole Cell Lysate
LYSATE0024 200ug
EUR 180
Description: This cell lysate is prepared from human mcf-7 using Boster's RIPA Lysis Buffer (AR0105) using a standard whole cell lysate protocol. The concentration was determined using the BCA assay process and then diluted using Dithiothreitol (DTT) and a reducing SDS sample loading buffer, heated for 5 minutes at 100˚C.
MCF 7 Membrane Lysate
XBL-10442 0.1 mg
EUR 619.8
Description: MCF 7 (Human breast Adenocarcinima) cell membrane protein lysate was prepared by isolating the membrane protein from whole tissue homogenates using a proprietary technique. The MCF 7 (Human breast Adenocarcinima) cell was frozen in liquid nitrogen immediately after excision and then stored at -70ºC. The membrane protein is provided in a buffer including HEPES (pH 7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the isolated MCF 7 (Human breast Adenocarcinima) cell membrane protein pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The isolated MCF 7 (Human breast Adenocarcinima) cell membrane protein is then Western analyzed by either GAPDH or β-actin antibody to confirm there is no signal or very weak signal.
MCF-7 Nuclear Extract
X12002 1000 µg Ask for price
Genomic DNA from Human Tumor Cell Line: MCF 7
D1255830 100 ug
EUR 291.6
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.
Total Protein from Human Tumor Cell Line: MCF 7
P1255830 1 mg
EUR 256.8
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.
Membrane Protein from Human Tumor Cell Line: MCF 7
P3255830 0.1 mg
EUR 342
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.
Paraffin Tissue Section - Human Tumor Cell Line: MCF-7
T2255830 5 slides
EUR 308.4
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.
Total RNA from Human Tumor Cell Line: MCF 7
R1255830-50 50 ug
EUR 232.8
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.
MCF-7 Nuclear Extract (H2O2)
1642-100
EUR 248.4
Human MCF-7 (breast cancer) Cell Nuclear Extract
HCL-2016 100ug
EUR 255.6
AAV2-Luc Control Virus
AAV-320 50 ?L
EUR 1221.6
Description: Luciferase control virus of AAV serotype 2.
AAV1-Luc Control Virus
AAV-321 50 ?L
EUR 1221.6
Description: Luciferase control virus of AAV serotype 1.
AAV3-Luc Control Virus
AAV-323 50 ?L
EUR 1221.6
Description: Luciferase control virus of AAV serotype 3.
AAV4-Luc Control Virus
AAV-324 50 ?L
EUR 1221.6
Description: Luciferase control virus of AAV serotype 4.
AAV5-Luc Control Virus
AAV-325 50 ?L
EUR 1221.6
Description: Luciferase control virus of AAV serotype 5.
AAV6-Luc Control Virus
AAV-326 50 ?L
EUR 1221.6
Description: Luciferase control virus of AAV serotype 6.
Human AsPC1 / Luciferase Cell Line
SC062-Luc 2 x 106 cell/ml x 1ml
EUR 1800
Description: Firefly luciferase expression stable cell line in Human AsPC1 cells with Puromycin resistance
mouse MOPC315 / Luciferase Cell Line
SC063-Luc 2 x 106 cell/ml x 1ml
EUR 2670
Description: Firefly luciferase expression stable cell line in mouse MOPC315 cells with Puromycin resistance
MCF-7 Whole Cell Lysate (Human breast adenocarcinoma cells)
MCF7-100 100 ug
EUR 196.8
MCF-7 Whole Cell Lysate (Human breast adenocarcinoma cells)
MCF7-50 50 ug
EUR 153.6
A549 / Luciferase (Puromycin) stable cell line
SC043-Luc 2 x 106 cell/ml x 1ml
EUR 1104
Description: Luciferase (firefry) expression stable cell line in A549 human cancer cell line with Puromycin marker.
MCF-7 Human breast cancer, noninvasive cell line: >1x10^10 frozen exosomes
EXOP-100A-1 50 ug
EUR 560.4
  • Category: Exosomes
Human PANC-1 / Luciferase (Puro) Cell Line
SC068-Luc 2 x 106 cell/ml x 1ml
EUR 2670
Description: Firefly luciferase expression stable cell line in Human PANC-1 cells with Puromycin resistance
MCF-10A
C0006015 One Frozen vial
EUR 560.4
Human MCF-7 (breast cancer) Whole Cell Lysate, Hydrogen Peroxide Stimulated
HCL-2014 100ug
EUR 255.6
293AAV Cell Line
AAV-100 1 vial
EUR 609.6
Description: The 293AAV Cell Line is derived from the parental 293 cells but selected for attributes that increase AAV production, including firmer attachment and larger surface area.
293AD Cell Line
AD-100 1 vial
EUR 553.2
Description: The 293AD Cell Line is derived from the parental 293 cells but selected for attributes that increase adenovirus production, including firmer attachment and larger surface area.
293LTV Cell Line
LTV-100 1 vial
EUR 609.6
Description: The 293LTV Cell Line is derived from the parental 293 cells but selected for attributes that increase lentiviral production, including fimrer attachment and larger surface area.
293RTV Cell Line
RV-100 1 vial
EUR 609.6
Description: The 293RTV Cell Line is derived from the parental 293 cells but selected for attributes that increase retroviral production, including fimrer attachment and larger surface area.
293/GFP Cell Line
AKR-200 1 vial
EUR 686.4
Description: 293/GFP Cell Line stably expresses GFP and otherwise exhibits the same characteristics of the parental cell line.
T47D/GFP Cell Line
AKR-208 1 vial
EUR 686.4
Description: T47D/GFP Cell Line stably expresses GFP and otherwise exhibits the same characteristics of the parental cell line.
A549/GFP Cell Line
AKR-209 1 vial
EUR 686.4
Description: A549/GFP Cell Line stably expresses GFP and otherwise exhibits the same characteristics of the parental cell line.
HeLa/GFP Cell Line
AKR-213 1 vial
EUR 686.4
Description: HeLa/GFP Cell Line stably expresses GFP and otherwise exhibits the same characteristics of the parental cell line.
NIH3T3/GFP Cell Line
AKR-214 1 vial
EUR 686.4
Description: NIH3T3/GFP Cell Line stably expresses GFP and otherwise exhibits the same characteristics of the parental cell line.
NIH3T3/Cas9 Cell Line
AKR-5104 1 vial
EUR 686.4
293/Cas9 Cell Line
AKR-5110 1 vial
EUR 686.4
HeLa/Cas9 Cell Line
AKR-5111 1 vial
EUR 686.4
Anti-Cytokeratin 7
DB051RTU-7 7 ml
EUR 244.8
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
pT7- Luc
PVT10670 2 ug
EUR 361.2
pSBE- Luc
PVT10816 2 ug
EUR 361.2
pTRE3G- LUC
PVT10818 2 ug
EUR 361.2
pAP1- Luc
PVT10819 2 ug
EUR 361.2
pHSE- Luc
PVT10820 2 ug
EUR 319.2
pGRE- luc
PVT10821 2 ug
EUR 319.2
pCRE- Luc
PVT10825 2 ug
EUR 361.2
pViperin- Luc
PVT10826 2 ug
EUR 361.2
pTA- Luc
PVT10827 2 ug
EUR 361.2
pTAL- Luc
PVT10829 2 ug
EUR 361.2
pIRF3- Luc
PVT10830 2 ug
EUR 361.2
p53- Luc
PVT10836 2 ug
EUR 319.2
pBV-Luc
PVT12245 2 ug
EUR 843.6
pMR-Luc
PVT14074 2 ug
EUR 843.6
OVCAR-5/RFP Cell Line
AKR-254 1 vial
EUR 686.4
Description: OVCAR-5/RFP Cell Line stably expresses RFP and otherwise exhibits the same characteristics of the parental cell line.
NF-kB/293/GFP-Luc Transcriptional Reporter Cell Line
TR860A-1 >2 x 10^6 cells
EUR 3915.6
  • Category: Lentiviral Technology
Recombinant Human Galectin-7
7-00442 2µg Ask for price
Recombinant Human Galectin-7
7-00443 10µg Ask for price
Recombinant Human Galectin-7
7-00444 1mg Ask for price
Recombinant Human Interleukin-7
7-00895 2µg Ask for price
Recombinant Human Interleukin-7
7-00896 10µg Ask for price
Recombinant Human Interleukin-7
7-00897 1mg Ask for price
Recombinant Mouse Interleukin-7
7-00904 2µg Ask for price
Recombinant Mouse Interleukin-7
7-00905 10µg Ask for price
Recombinant Mouse Interleukin-7
7-00906 1mg Ask for price
Recombinant Human Kallikrein-7
7-03034 2µg Ask for price
Recombinant Human Kallikrein-7
7-03035 10µg Ask for price
Recombinant Human Kallikrein-7
7-03036 100µg Ask for price
Recombinant ProMatrix Metalloproteinase-7
7-03478 5µg Ask for price
Recombinant ProMatrix Metalloproteinase-7
7-03479 20µg Ask for price
Recombinant ProMatrix Metalloproteinase-7
7-03480 1mg Ask for price
Individual Reaction Mix 7
G065-7 200 reactions
EUR 200.4
Recombinant Human Interleukin-7, Saccharomyces
7-00898 2µg Ask for price
Recombinant Human Interleukin-7, Saccharomyces
7-00899 10µg Ask for price
Recombinant Human Interleukin-7, Saccharomyces
7-00900 1mg Ask for price
Recombinant Human Matrix Metalloproteinase-7
7-03154 5µg Ask for price
Recombinant Human Matrix Metalloproteinase-7
7-03155 20µg Ask for price
Recombinant Human Matrix Metalloproteinase-7
7-03156 1mg Ask for price
Lung Lysate (7 Days Old)
1402-7 0.1 mg
EUR 229.2
Description: Lung tissue lysate (7 Days Old) was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 50 mM DTT.
Brain Lysate (7 Days Old)
1403-7 0.1 mg
EUR 229.2
Description: Brain tissue lysate (7 Days Old) was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 50 mM DTT.
Liver Lysate (7 Days Old)
1404-7 0.1 mg
EUR 229.2
Description: Liver tissue lysate (7 Days Old) was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 50 mM DTT.
Kidney Lysate (7 Days Old)
1405-7 0.1 mg
EUR 229.2
Description: Kidney tissue lysate (7 Days Old) was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 50 mM DTT.
Spleen Lysate (7 Days Old)
1406-7 0.1 mg
EUR 229.2
Description: Spleen tissue lysate (7 Days Old) was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 50 mM DTT.
Thymus Lysate (7 Days Old)
1409-7 0.1 mg
EUR 229.2
Description: Thymus tissue lysate (7 Days Old) was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 50 mM DTT.
Stomach Lysate (7 Day Old)
1415-7 0.1 mg
EUR 229.2
Description: Stomach tissue lysate (7 Day Old) was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 50 mM DTT.
Skin Lysate (7 Days Old)
1419-7 0.1 mg
EUR 229.2
Description: Skin tissue lysate (7 Days Old) was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 50 mM DTT.
Eye Lysate (7 Days Old)
1420-7 0.1 mg
EUR 229.2
Description: Eye tissue lysate (7 Days Old) was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 50 mM DTT.
ICP Quality Control Standard 7
QC-7 125ML
EUR 176.7
Platinum-E Retroviral Packaging Cell Line, Ecotropic
RV-101 1 vial
EUR 1104
Description: Conventional cells used for retrovirus packaging, such as those based on NIH3T3 cells, have limited stability and produce relatively low yields of retrovirus, mainly due to the poor expression of retroviral structure proteins (gag, pol and env) in the cells. The Platinum Retroviral Packaging Cell Lines are based on the 293T cell line. They exhibit longer stability and produce higher yields of retroviral structure proteins. Plat-E cells contain gag, pol and env genes, allowing retroviral packaging with a single plasmid transfection.
Platinum-A Retroviral Packaging Cell Line, Amphotropic
RV-102 1 vial
EUR 1104
Description: Conventional cells used for retrovirus packaging, such as those based on NIH3T3 cells, have limited stability and produce relatively low yields of retrovirus, mainly due to the poor expression of retroviral structure proteins (gag, pol and env) in the cells. The Platinum Retroviral Packaging Cell Lines are based on the 293T cell line. They exhibit longer stability and produce higher yields of retroviral structure proteins. Plat-A cells contain gag, pol and env genes, allowing retroviral packaging with a single plasmid transfection.
Platinum-GP Retroviral Packaging Cell Line, Pantropic
RV-103 1 vial
EUR 1104
Description: Conventional cells used for retrovirus packaging, such as those based on NIH3T3 cells, have limited stability and produce relatively low yields of retrovirus, mainly due to the poor expression of retroviral structure proteins (gag, pol and env) in the cells. The Platinum Retroviral Packaging Cell Lines are based on the 293T cell line. They exhibit longer stability and produce higher yields of retroviral structure proteins. Plat-GP cells contain the gag and pol genes required for retroviral packaging; an expression vector is co-transfected with a VSVG envelope vector.
pUC57-Tac-Luc
PVT18215 2 ug
EUR 309.6
p21-Luc Plasmid
PVTB00035-2c 2 ug
EUR 427.2
IgK- IFN- luc
PVT10425 2 ug
EUR 319.2
pNFAT- TA- Luc
PVT10808 2 ug
EUR 319.2
pE2F- TA- Luc
PVT10809 2 ug
EUR 319.2
pISRE- TA- Luc
PVT10810 2 ug
EUR 319.2